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CBD for Inflammation: Does it Really Work?

November 26, 2021

Do you suffer from acute or chronic inflammation and need relief? Have you considered using CBD for inflammation? If not, you should start now!

What is CBD? Cannabidiol, CBD, is an active cannabinoid that's naturally found in the cannabis plant. This cannabinoid doesn't give you a "high" - instead, it relaxes your mind and body. 

CBD is commonly used to treat medical conditions, but does CBD help with inflammation? 

Continue reading to find out about all the wonderful benefits and if CBD is an anti-inflammatory. 

CBD oil and cream
CBD oil and cream

Is CBD an anti-inflammatory?

Before we can talk about anti-inflammatory CBD, we need to address what inflammation is. 

Inflammation is when your body fights off an infection from a virus or bacteria with white blood cells. 

Acute inflammation happens when you have a small injury, like when you twist your ankle, have a cut, or have a sore throat. Chronic inflammation comes from severe conditions like cancer, arthritis, diabetes, or Alzheimer's disease. 

An anti-inflammatory is a substance that reduces swelling, stiffness, redness, pain, and discomfort caused by inflammation. Common pharmaceutical anti-inflammatories include aspirin and ibuprofen. 

Is CBD an anti-inflammatory? Yes, CBD is an anti-inflammatory. 

It’s an anti-inflammatory because it interacts with the body's endocannabinoid system, regulating functions like immune system response, pain, appetite, and sleep. 

How does CBD reduce inflammation?

Our anatomy makes endocannabinoids (neurotransmitters that connect to cannabinoid receptors in the nervous system). Cannabinoids, like CBD, enter the body when you consume marijuana. 

These cannabinoids are known to interact with the cannabinoid receptors naturally found in our bodies. Cannabinoid receptors include CB1, which is found in the brain. This is why CBD for depression and CBD for migraines is so effective. 

CB2, which is found in our immune system, is another cannabinoid receptor. Cannabinoids help regulate our immune systems through the interaction with cannabinoid receptors. 

Anti-inflammatory CBD helps reduce inflammation and aids autoimmune diseases because the endocannabinoid receptors are more active and can do their jobs better. 

Cannabis medical oil
Cannabis medical oil

How effective is CBD for inflammation?

There have been plenty of studies about CBD and inflammation on animals and humans.Real-life experiences prove it's effective and, in some cases, natural CBD is more effective than chemical pharmaceutical drugs. 

In 2017,  scientists did a study using CBD for inflammation on rats with induced osteoarthritis. The rats were then given a local CBD treatment. The results found that CBD blocked osteoarthritis pain and nerve damage in joints. 

In 2015, the US National Library of Medicine National Institutes of Health published that CBD has promising therapeutic effects for epilepsy, an autoimmune disease. 

Cheyanne, a social media influencer, was diagnosed with stage 4 ovarian cancer at the age of 23. She experienced the horrible side effects and reached for CBD for inflammation relief. After a few days, she wasn't nauseous or anxious, and her insomnia went away

There are enough scientific and real-life stories out there to say that CBD for inflammation is an effective choice. 

How to use CBD for inflammation?

There are a few ways you can use CBD for inflammation, and they all have their perks. 

The most traditional way is to smoke the herb of high-CBD strains. The risk with this is the combustion from smoking isn't great for your health. You'll still get the benefits of the CBD, but it can cause a sore throat or other health conditions. 

Consider buying the CBD Harlequin marijuana strain for therapeutic benefits. This cannabis crop contains 18% CBD and 1% THC. When consumed, it's one of the best CBD strains for inflammation. 

Products derived from the buds grown from CBD Tangie feminized seeds are another great option. The crop is mostly sativa, contains 15% CBD, and only 1% THC. You can consume this strain during the day because it won't put you to sleep. 

You can also use CBD for inflammation in the form of oils. CBD oil consists of CBD that's derived from the marijuana plant and then blended with a carrier oil. 

To use it, you can squeeze a few drops under your tongue where the product quickly absorbs into your bloodstream.. You can also use CBD oil for inflammation in foods to make edibles. 

CBD oil for inflammation is also sold in capsules so that you can take it as a pill. 

CBD topicals are made by extracting CBD from cannabis and mixing it with a cream or lotion. You can apply CBD for inflammation directly on the areas that are causing pain. CBD topicals can help with redness and swelling as well. 

Smoking cannabis
Smoking cannabis

How long do the CBD's anti-inflammatory properties take to work?

When looking at the time it takes to feel relief when you consume CBD for inflammation, you need to consider how you're taking it. Smoking, ingesting, or applying CBD to the skin all have different activation times. 

If you smoke CBD anti-inflammatory weed strains, you'll start to feel the effects within minutes. The maximum intensity will come within half an hour. The effects will last for about 6 hours. 

When you ingest CBD oil for inflammation under your tongue, it's absorbed in about 30 seconds, and you'll feel the effects within 15 minutes

Consuming edibles or swallowing capsules will take longer to kick in. The maximum intensity hits about 45 minutes to 2 hours after you eat it. Be careful not to over-consume edible CBD for inflammation, which happens when you're impatient. 

If you use topical CBD for inflammation, you'll feel the effects within 15 minutes of applying. 

Are there any side effects associated with marijuana for inflammation?

Is weed anti-inflammatory, and does it cause side effects? Yes, there are some side effects when you use CBD for inflammation, but they're mild. Let's take a look at the major ones. 


CBD is known to chill out the mind and body. When CBD is used for inflammation, the immune system's activity is slowed down to reduce the swelling, pain, redness, or heat. 

These effects are exactly what you want, but CBD also can affect your brain. The sedative quality of CBD for inflammation can make you tired

If sleepiness affects your daily life, you might need to reduce the amount of CBD oil for inflammation you're taking during the day and up your dosage at night. 


CBD is an anti-inflammatory and can aid in nausea caused by cancer treatments or heavy medications because it interacts with serotonin receptors. 

That being said, some who take CBD for inflammation might experience nausea as a side effect. You might be thinking, well, how can CBD help and cause stomach sickness? 

If CBD for inflammation is taken on an empty stomach or you take too much at one time, you could experience nausea. It's best to take your supplements with food and water to reduce these side effects. 

Gastrointestinal Issues

A common side effect of using CBD for inflammation is gastrointestinal issues or diarrhea. Why does this happen? 

CBD oils for inflammation interact with your endocannabinoid system, which reduces excess gastric acids, increases blood flow to the digestive lining, and helps the lower esophagus to prevent acid reflux. 

The CBD can speed up your digestive tract, which leads to diarrhea. After the first couple of weeks of using CBD for inflammation, these side effects should calm down. If they don't, talk to your doctor because you might need to lower your dosage. 

Dry mouth

Although not a serious side effect from CBD for inflammation, dry mouth sure is annoying, unpleasant, and could lead to other more serious problems. 

Also known as "cottonmouth," this happens because the anti-inflammatory CBD affects cannabinoid receptors found in the submandibular glands. These glands produce saliva. 

The CBD for inflammation reduces the activity of salivary production, which results in dryness. To help cope with this side effect, be sure to drink plenty of water before, during, and after taking CBD oil for inflammation. 

Low blood pressure

When you take a high dose of CBD for inflammation, you can experience lower blood pressure because of the sedative qualities. If your blood pressure drops too low too quickly, you can feel lightheaded or faint. 

Although lower blood pressure isn't a bad thing (many people need to reduce theirs), the passing out and dizziness could lead to other injuries. Never take a high dose of CBD for inflammation before driving a car or leaving the house alone. 

Interaction with other medications

If you're taking CBD for inflammation, you might be on other types of medications as well. It's vital to talk to your doctor about how anti-inflammatory CBD could interact with the other medications

When your medications have the grapefruit warning, proceed with caution with CBD for inflammation. CBD and grapefruits interact with cytochromes, which are enzymes that are essential to drug metabolism. 

Possible liver toxicity

When you're taking a large dose of CBD for inflammation for a long time, you can have some liver problems. 

In a study with rats, there were clear signs of liver toxicity when they were given a high dose of CBD for inflammation. The rats that took a smaller dose of CBD also showed signs of liver damage and swelling. 

The amount of CBD for inflammation the rats were given was much more than most humans would ingest. It's always crucial to follow your doctor's recommendations on the amount of anti-inflammatory CBD you take to avoid these side effects. 

CBD oil for inflammation
CBD oil for inflammation

Best CBD for inflammation: how to choose the right product for you?

What might be perfect for one person doesn't mean it'll be right for you. Talk to your doctor about your specific needs and concerns about using CBD for inflammation. 

CBD oils for inflammation and other edibles and dry herb enter your body and affect your entire body. CBD topicals enter through the skin and provide direct relief where you apply them. 

Once you figure out what type of relief you want from CBD for inflammation, you should also think about these factors. 

Hemp sourced vs. cannabis sourced

Federally, hemp sourced CBD oil for inflammation with less than 0.3% THC is legal. In some states, medical cannabis-derived products remain illegal. You have to understand what your state laws are to know which products you can buy. 

Extract type

There are three types of CBD for inflammation that can be extracted to make medical CBD oils. 

The first is CBD isolate, which is pure CBD. The next is broad-spectrum CBD extract, which contains terpenes, other cannabinoids, fatty acids, flavonoids, and other plant material. Broad-spectrum CBD for inflammation doesn't contain THC. 

The third extract is full-spectrum CBD, which takes all of the broad spectrum extracts along with THC. There are medical benefits for THC also, so talk with your doctor about which anti-inflammatory CBD extract is best for you. 


Not all CBD for inflammation products have the same potency. As you might think, the more potent, the more you'll feel the effects and vice versa. Talk to your doctor about your recommended dosage to help you choose which CBD oils for inflammation you should buy. 


CBD oils for inflammation come in different tastes. Some are more natural, others are artificials, and some try to eliminate all flavors. If you're going to  CBD for inflammation every day, it should be something that you enjoy ingesting. 

If you're in a house with children around and you have kid-friendly flavors like bubblegum, fruits, or dessert items, you need to keep your CBD oils for inflammation locked up

Added ingredients

Anti-inflammatory CBD products are mixed with other ingredients. You must know exactly what's in your supplements. You could have an allergic reaction, or the ingredients could interact with your other medications. 

It's best to look for natural and organic ingredients for your CBD for inflammation. Extra chemicals, sugars, and colorings won't help your medical condition. 

Lab results and brand reputation

Most people don't want to be the guinea pig when testing medical treatments, and the same goes for CBD for inflammation products. Before consuming a new CBD item, do some research or ask your doctor. 

Look for a reputable company that has tested its products, maintains good customer testimonies, and has good customer service.

Take a look at their website, return policies, shipping process, and more to understand if the company is up to your standards. 

CBD edibles
CBD edibles

What is the average CBD dosage for inflammation?

Your CBD dosage for inflammation depends on a few factors. You have to take a look at your body weight and size, your body's chemistry, the condition you're treating, and the concentration of CBD in the product you choose to use. 

It's always better to start with a lower amount and increase if needed. Starting with 10 to 20 milligrams a day is not too intense, but you'll feel the effects. The highest safe amount of CBD for inflammation you can take is 1,500 milligrams.

The World Health Organization reported that most medical CBD users take from 100 to 800 milligrams a day. 

Disclaimer: You should always talk to a doctor or medical professional before using CBD for inflammation. These dosages are based on averages and shouldn’t be used as professional medical advice. 

What are the best strains of CBD for inflammation?

There are marijuana strains that are naturally high in CBD to increase the medical benefits. Let's look at some CBD for inflammation strains from the Wellness Collection at Homegrown Cannabis Co

CBD 1-CA Ratio 1:20 Feminized

  • Mostly indica
  • THC: 1%
  • CBD: 20%

The herb grown from CBD 1-CA Ratio 1:20 feminized seeds is a powerful treatment for inflammation. The high percentage of anti-inflammatory CBD relieves your body of all tension. The indica effects will help you relax mentally, leaving you in a state of pure bliss

The THC is so low that it's hardly detected, making this a great option for treatments with CBD for inflammation. Use with caution during the day as the sedative effects could be dangerous when out and about. 

CBD 1-CA Ratio 1:20 Feminized
CBD 1-CA Ratio 1:20 Feminized

MediBerry Feminized 

  • Mostly indica
  • THC: 5%
  • CBD: 15%

The products derived from the plant of MediBerry feminized seeds are highly therapeutic. You'll get a slight cerebral buzz from the THC, which can clear the mind of stress or worry resulting from your medical condition. 

The main benefit of the strain is the anti-inflammatory CBD which melts your body into a weightless stress-free state. The physical and mental relief lifts your mood and helps you get through the day with happiness. 

MediBerry Feminized
MediBerry Feminized

CBD Blueberry Feminized 

  • Mostly indica
  • THC: 1%
  • CBD: 16%

If you're going to smoke your CBD for inflammation, the dry herb from CBD Blueberry feminized seeds is the way to go. The smoke is like a sweet, fresh blueberry pie. When consumed, you'll instantly be in a euphoric state. 

Your body will feel overwhelmingly calm because of the anti-inflammatory CBD. You won't feel any tension, and you'll be totally chilled out. 

CBD Blueberry Feminized
CBD Blueberry Feminized

CBD Strawberry Kush Feminized 

  • Mostly indica
  • THC: 0.5%
  • CBD: 9%

If your inflammation doesn't require an intense amount of anti-inflammatory CBD to work, look for products made from the harvest of CBD Strawberry Kush feminized seeds. With only 9% CBD, it creates soothing, mild relaxation. 

This is a perfect strain to use during the day, since the sedating qualities aren't too overwhelming. Don't be fooled, though; this anti-inflammatory CBD strain relieves mental and physical stress to make you feel brand new again. 

CBD Strawberry Kush Feminized

CBD ACDC Feminized 

  • Mostly sativa
  • THC: 1%
  • CBD: 18%

If you're looking for a high anti-inflammatory CBD strain that's not as sedating, the plant from CBD ACDC feminized seeds is right for you. Since it's sativa-dominant, there's more of an energized effect. 

That being said, the 18% CBD, still leaves your body in a state of ultimate relaxation. Your mind will be clear and ready to focus while your anatomy feels tension-free, ready to move without pain. This is a great wake-and-bake medical cannabis strain. 

Final Points about cannabinoids and inflammation

Inflammation is a side effect of many serious medical conditions, which can make the pain feel worse and everyday activities uncomfortable. CBD for inflammation is a natural way to gain relief. 

Let’s look at some key takeaways on cannabinoids and inflammation. 

  • CBD is an anti-inflammatory. 
  • CBD for inflammation has proven highly effective in both studies and real-life. 
  • Anti-inflammatory CBD can be consumed by smoking, ingesting, or topically. 
  • CBD for inflammation kicks in anywhere from 15 minutes to two hours after consumption. 
  • CBD can cause side effects, so you should always talk to a doctor before using it. 
  • Choosing the correct anti-inflammatory CBD product is based on personal needs. 
  • The beginner dose is 20 milligrams of CBD for inflammation a day. 
  • Find the best CBD strains for inflammation at Homegrown Cannabis Co. 

With medical cannabis legal in 36 states and CBD oil with less than 0.3% THC legal federally, you should consider using CBD products to help fight inflammation today. What's the wait? Contact your doctor and start growing your own plants to make CBD for inflammation now.

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