10 Best Hybrid Strains To Grow In 2021

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hybrid strains
Author avatar By Derek LaRose
October 13, 2021
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Cultivators that choose to grow hybrid strains enjoy the balanced effects they provide. That’s not to say each cultivar is the same, as you can experience a plethora of sensations depending on which cannabis seed you plant.

To make your search that much easier, we’ve put together a list of the best hybrid strains in 2021. You’ll find a description of each type, as well as where to purchase these majestic marijuana seeds

Let’s get started!

Black Widow Feminized strain
Black Widow feminized strain

What are hybrid strains?

Before we get stuck into our list of hybrid strains, it’s worth exploring this type of cannabis to better appreciate its brilliance. Created by marijuana breeders, this type of weed comes to life by mixing two or more indica and sativa strains.    

The marijuana plant’s physical characteristics will often resemble that of its dominant parent. If your seeds grow into short, broad-leaved plants, they’ll fall under indica-dominant hybrid strains. It´ll also produce a similar high to its presiding parent, with a few twists and turns thrown in.

On the other side of the hybrid strains spectrum, you can sow weed seeds that mature into tall cannabis plants with leaves resembling long, pointed fingers. They would also produce less dense buds but in no way less potent. Cultivators recognize this type of variety as sativa-dominant hybrid strains.

It’s not only a mixture of sativa and indica strains that we can enjoy. Hybrid strains can also offer cannabis growers a plant that pays no heed to the sunlight. These cultivars contain ruderal genetics and fall under the autoflower seeds category. They grow faster but at the expense of yield.

Some of the best hybrid strains break the shackles of THC and CBD percentages, allowing breeders to create truly potent specimens. Some varieties can even contain an equally high ratio of the two cannabinoids. This has allowed more individuals to benefit from hybrid strains, both recreationally and medically.

What are the effects of hybrid strains?

Rather than having to choose between the effects of sativa vs. indica, you can get the best of both worlds with hybrid weed strains. As we’ve mentioned, each cultivar offers both growers and users a range of effects.

As a recreational smoker, you’ll discover a treasure trove of exciting effects with hybrid strains. Some cultivars give you a relaxed and calming feeling while still allowing you to cope with everyday tasks.

These indica hybrid strains pair exceptionally well with music and movies. They help to emphasize emotions and provide a new perspective on issues that trouble you. These hybrid cannabis strains are also fantastic for intimate social gatherings acting as a social lubricant.

Other cultivars bring on feelings of excitement and mental clarity. If this is your aim, then you’ll want one of the many sativa hybrid strains. This variety is perfect for artists as it encourages creativity on another level.  

You’ll notice an energetic sensation gradually increase in your body like a strong caffeine buzz. This electric rollercoaster slowly comes to an end, leaving you smiling and satisfied. The only question remaining in your mind is if you should prepare for round two. 

Marijuana hybrid strains aren’t just for those wanting to get high. Medical cannabis continues to get the attention of individuals seeking an alternative treatment. Whether it’s to combat stress, depression, anxiety, or pain, hybrid strains have your back. 

What’s more, some popular hybrid strains contain almost zero THC. These varieties provide users with all the health benefits of cannabis, without the mental high.

There’s almost no end to the vast number of different effects possible with hybrid strains. Throw in the abundance of tastes and smells, and you begin to realize why this type of cannabis has taken the world by storm.

Hybrid cannabis strains
Hybrid cannabis strains

What are the best hybrid strains?

Over the years, hybrid strains have taken over the cannabis market. Their varied effects now attract a wide range of smokers and cultivators around the globe. We’ve put together a list of the top 10 hybrid strains available today to make your search for cannabis seeds that much easier.

1. Black Widow Feminized

Not only is the Black Widow strain one of the strongest varieties available, but it’s also simple to grow, making it fantastic for beginners. It offers a generous yield, especially when placed inside a greenhouse setup, with delicious buds containing THC levels around 25%.

As one of the top hybrid strains, you can expect feelings of euphoria and relaxation throughout your body. It’s dominated by terpinolene terpene, giving off a sweet pine and fruity flavor. Black Widow Feminized is a prime example of 50/50 hybrid strains, producing a balance of energetic and calming sensations.

Black Widow
Black Widow

2. Grape Killer 99 Feminized

The Grape Killer 99 Feminized is a sativa leaning hybrid perfect for those looking to socialize in an upbeat manner. As soon as it hits your lips, your brain takes off, encouraging positive emotions that stimulate your mind while soothing your body. It’s also one of the best outdoor strains for beginners, producing over 14 ounces per plant.

This cultivar offers an assortment of flavors such as grape, citrus, and sweet earthy tones. These tastes remain stuck to your pallet as your eyes begin to pick up vivid colors from your surroundings. Your journey then tapers at the end, leaving you slightly drowsy.

Grape Killer 99
Grape Killer 99

3. Amnesia Kush Feminized

The Amnesia Kush Feminized comes from crossing two legendary cultivars, OG Kush and Amnesia Haze. Its high THC levels usually sit around 18%, producing effects in line with its sativa genetics.

As you begin to appreciate this cultivar’s sweet yet spicy citrus flavor, it brings on feelings of creativity and focus. This euphoric flame erupts in your mind, similar to other strong sativa leaning hybrid strains. Those with a low tolerance should proceed with caution with this bud, as this high can become overwhelming.

Amnesia Kush
Amnesia Kush

4. Gangster Sourz Feminized

If you’re looking for hybrid marijuana strains that offer a balance of calming and energizing feelings, this one’s for you: Gangster Sourz Feminized. Packed with kerosine and pine flavors, the cross between Sour Diesel and OG Kush strain explodes in your mouth.

As soon as it touches your lips, you should feel your mind fill up with positivity, and your imagination wander. Ideas flow effortlessly, making this cultivar a hit amongst creatives and those looking to unlock some inspiration.

Gangster Sourz Feminized
Gangster Sourz Feminized

5. Northern Cream Auto

While some hybrid strains rely on the warm summer season to grow, others will mature all year round. A cross between Northern Lights strain and Cream strain, Northern Cream Auto is a fabulous example of autoflowering perfection. Its hardy nature makes it tolerant of inexperienced hands and usually produces around five ounces of bud per cannabis plant.

As its sweet earthy tones take hold of your taste buds, you can expect an intense euphoria beginning at the back of your skull. It mixes well with social gatherings, as you find yourself giggling at anything and everything. As these happy feelings subside, you might want to grab a few healthy snacks as the munchies come out of nowhere.

Northern Lights x Cream
Northern Cream Auto

6. CBD Cheese Autoflower

Nothing says wellness like the scent of sweet, fresh flowers. The CBD Cheese Autoflower is everything you’ll need for a balanced medicinal hybrid cultivar. You can grow it all year round, but it requires some experience to ensure a quality crop.

Its high CBD levels are perfect for treating anxiety and muscle spasms but with very mild psychedelic effects. The pungent cheddar flavors fill your mouth with delicious goodness as it calms your body after a long day.

CBD Cheese
CBD Cheese

7. Sour Skies Feminized

Sour Skies is one of the best indoor strains on the market, providing cultivators with up to 1.6 ounces per square foot in a greenhouse environment. It’s known for its bitter citrus flavors inherited from its Sour Diesel parent.

The Sour Skies Feminized tends to evoke feelings of calm and relaxation while still energizing your mind. Its sativa properties first make themselves known, catapulting you into a powerful state of bliss. Tranquility then washes over your body, rooting you to your couch, similar to other indica hybrid strains.         

Sour Skies
Sour Skies

8. Rosetta Stone Feminized

The Rosetta Stone Feminized is a smorgasbord of delicious flavors sure to get your mouth watering. You can expect fruity notes like apricot and citrus with highlights of pine and aromatic spices. It’s best categorized amongst other 50/50 hybrid strains, growing buds that contain up to 19% THC.

Cultivating these cannabis seeds will require some experience from your side as it’s vulnerable to bud rot. Upon ingesting its smooth smoke, you should prepare for a mental clarity like no other. It’s a terrific option for those looking for a cultivar that gives you energy throughout your day.

Rosetta Stone
Rosetta Stone

9. Girl Scout Cookies Feminized

There’s nothing better than starting your day with the Girl Scout Cookies strain. It summons a powerful mental exhilaration that enhances your mood, unlocking an optimistic mindset. This cultivar is perfect for medicinal and recreational smokers alike, making it one of the best hybrid strains out there.

Those with anxiety, depression, and migraines will benefit most from the high THC buds. The Girl Scout Cookies Feminized is also great before a meal as it elevates your desire for food. If your tolerance is low, you might feel the need to have a short power nap after this smoke, so proceed with caution.

Girl Scout Cookies
Girl Scout Cookies

10. Blue Jack City Auto

The Blue Jack City Autoflower is potentially one of the most beautiful cannabis plants on the market. Cultivators of all skill levels can enjoy watching succulent green colas emerge from their purple leaves. You’re then greeted by sweet berry and lemon smells that are reinforced on your pallet.

This marijuana plant produces THC levels around the 20% mark, initially transporting your brain to paradise. You’ll then notice your energy levels rise, allowing you to make light work of any challenge that presents itself. This turns into calm as it begins to soothe any tension in your body.

Blueberry x Jack Herer
Blueberry x Jack Herer

A win-win situation

With so many options to choose from, it’s clear just how many people benefit from hybrid strains. Some cultivars contain that missing element allowing you to start your day right. Other varieties help you to unwind after a stressful day and soothe your aching muscles.

Now that you have a list of the best hybrid strains for 2021, you can start planning your next grow. Purchase your seeds from Homegrown Cannabis Co. today and experience these amazing benefits yourself.


About the author: Derek LaRose

Also known as Kronic from The Cannabis Kronicles, Derek LaRose is a young ambitious cultivator and a staple educator for indoor cultivation.